PLASMAPROLACTIN IN DER VERSCHIEDENEN ALTERSSTUFEN

Abstract

After a detailed introduction to the problems of radioimmunological measurement of Prolactin and a review of the possible connections between PRL and urological and andrological diseases, respectively, the results of Prolactin measurements carried out with a Prolactin Radioimmunoassay Kit (Cea-Ire-Sorin) are described. This Kit makes use of the 'double antibody' method. In 99 healthy male subjects the plasma levels of Prolactin in 3 age groups were ascertained. These were as follows: Group I ages 10 to 20: 2.4 ± 1.2 ng/ml; group II ages 20 to 40: 3.9 ± 1.5 ng/ml; group III ages 50 to 80: 5.2 ± 3.8 ng/ml. In the case of 10 patients suffering from Sertoli cell only syndrome, the mean level of PRL was: 3.08 ± 2.14 ng/ml. In the cases of 4 patients suffering from prostate cancer stage D, treated with hormones at various intervals and after orchiectomy the range of PRL levels was 13.1-18.7 ng/ml.