The human intestinal tract is inhabited by trillions of microorganisms and houses the largest pool of macrophages in the human body. Being a part of the innate immune system, the macrophages, the professional phagocytes, vigorously respond to the microbial and dietary antigens present in the intestine. Because such a robust immune response poses the danger to the survival of the non-harmful and beneficial gut microbiota, the macrophages developed mechanisms of recognition and hyposensitivity toward the non-harmful/beneficial inhabitants of the gut. We will discuss the evolution and identity of some of these mechanisms in the following chapter.
CITATION STYLE
Kloc, M., Uosef, A., Elshawwaf, M., Abdelshafy, A. A. A., Elsaid, K. M. K., Kubiak, J. Z., & Ghobrial, R. M. (2020). The Macrophages and Intestinal Symbiosis. In Results and Problems in Cell Differentiation (Vol. 69, pp. 605–616). Springer Science and Business Media Deutschland GmbH. https://doi.org/10.1007/978-3-030-51849-3_23
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