Delivery of an active lysosomal enzyme using GNeosomes

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Abstract

Two methods for assembling guanidinoneomycin-decorated liposomes are presented and their ability to deliver an active enzyme to the lysosomes and restore enzyme function in diseased cells is compared.

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Hamill, K. M., Wexselblatt, E., Tong, W., Esko, J. D., & Tor, Y. (2016). Delivery of an active lysosomal enzyme using GNeosomes. Journal of Materials Chemistry B, 4(35), 5794–5797. https://doi.org/10.1039/c6tb01387b

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