Topics in Nucleic Acids Structure: DNA Interactions and Folding

Abstract

This chapter introduces further topics in nucleic acid structure, building upon the minitutorial of the previous chapter. These topics include DNA sequence effects, DNA hydration, DNA/protein interactions, and the cellular organization of DNA,including supercoiling and chromatin structure. The next chapter expands upon the related topics of alternative hydrogen bonding schemes, non-canonical helical and hybrid structures, DNA mimics, overstretched and understretched DNA, andRNA structure and folding.