Retinal pigment epithelial change and partial lipodystrophy

17Citations
Citations of this article
7Readers
Mendeley users who have this article in their library.

Abstract

Cuticular drusen and retinal pigment epithelial changes were found incidentally in a 27 year old Lebanese woman during assessment of partial lipodystrophy. Her vision was normal despite involvement of both maculae. The patient had hypocomplementaemia, but serum C3 nephritic factor was absent and renal function was normal. She had impaired glucose tolerance and a continuous infusion of glucose with model assessment (CIGMA) test revealed low normal tissue insulin sensitivity and high normal pancreatic beta cell function. Mild fasting hypertriglyceridaemia (2.0 mmol/l) may have been secondary to impaired insulin sensitivity. Endocrine function was otherwise normal apart from a completely absent growth hormone response to adequate hypoglycaemia. The simultaneous occurrence of partial lipodystrophy and retinal pigmentary epithelial and basement membrane changes appears to be a newly recognized syndrome.

Cite

CITATION STYLE

APA

Davis, T. M. E., Holdright, D. R., Schulenberg, W. E., Turner, R. C., & Joplin, G. F. (1988). Retinal pigment epithelial change and partial lipodystrophy. Postgraduate Medical Journal, 64(757), 871–874. https://doi.org/10.1136/pgmj.64.757.871

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free