STUDY ON PHARMACEUTICAL DEVELOPMENT AND QUALITY CONTROL OF ANTIBIOTIC INJECTION ADMINSTRATION BY PERENTRAL ROUTE FOR PUBLIC HEALTH CARE.

Abstract

Objective of this review article to give detail about antibiotic used as parenteral route of administration in injection forms. Antibiotics history began with the observations made by Sanderson and Roberts on the inhibition of bacterial growth by other organisms, at the end of the XIX Century. Biomedical research in this field advanced importantly during World War II, after the discovery of penicillin by Fleming. Now-a-days the number of antibiotics plays an important role in the society particularly animal and human life. A series of different antibodies were quickly discovered after penicillin came into use. In 1940, Selman Waksman began searching for antibiotic compounds produced by soil microorganisms. In 1943, one of Waksman's student discovered streptomycin, leading to a flood of researchers combing that world for new drugs. It was in this same period that Rene Dubos discovered gramicidin, the first antibiotic active against gram-positive bacteria. Many discoveries were of drugs that were too toxic for human use, or that had already been discovered. Injection as antibiotic are administration by parenteral route. It gave more accurate and efficient on set of action to the patients.