Boric Acid: A Versatile Catalyst in Organic Synthesis

Abstract

In recent years, the concept of synthesis of organic compounds follows green chemistry principle in order to minimize environmental hazards caused due to organic solvents. Thus to implement an environment-friendly approach, researchers stand in a need of water-compatible catalysts in order to establish a library compound of pharmacologically important moieties with distinct properties. Exceptional interest of researchers gained by the boric acid owing to its easy commercial availability, eco-friendly physicochemical properties. It is recently proven to be a good substitute for conventional acidic catalytic materials. Boric acid successfully catalysed various organic conversions useful in day-to-day chemistry lab such as addition, esterification, substitution and condensation type of reactions. Additionally, boric acid is also useful in numerous multicomponent reactions involved in the synthesis of various biologically important heterocycles.