Clinical application of auto-tooth bone graft material

Abstract

(J Korean Assoc Oral Maxillofac Surg 2012;38:2-8) Introduction: Auto-tooth bone graft material consists of 55% inorganic hydroxyapatite (HA) and 45% organic substances. Inorganic HA possesses properties of bone in terms of the combining and dissociating of calcium and phosphate. The organic substances include bone morphogenetic protein and proteins which have osteoinduction capacity, as well as the type I collagen identical to that found in alveolar bone. Auto-tooth bone graft material is useful as it supports excellent bone regeneration capacity and minimizes the possibility of foreign body reaction,genetic diseases and disease transmission. Materials and Methods: Implant placement combined with osteoinductive regeneration,preservation of extraction socket, maxillary sinus augmen-tation, and ridge augmentation using block type,powder type, and block+powder type autobone graft materialwere performed for 250 patients with alveolar bone defect and who visited the Results: Clinical assessment: Among the 250 patients of auto-tooth bone graft, clinical assessment was performed for 133 cases of implant placement. The average initial stabilization of placed implants was 74 implant stability quotient (ISQ). Radiological assessment: The average loss of crestal bone in the mandible as measured 6 months on the average after the application of prosthesis load was 0.29 mm, ranging from 0 mm to 3.0 mm. Histological assessment: In the histological assessment, formation of new bone, densified lamellated bone, trabecular bones, osteoblast, and planting fixtures were investigated. Conclusion: Based on these results, we concluded that auto-tooth bone graft material should be researched further as a good bone graft material with osteoconduction and osteoinduction capacities to replace autogenous bone, which has many limitations. [paper submitted 2012. 1. 13 / revised 2012. 2. 6 / accepted 2012. 2. 6] R&D Center, and has satisfied many clinicians and patients for its osteoconduction as well as osteoinduction capacity. Auto­tooth bone graft material consists of 55% inorganic and 45% organic substances. Among the inorganic sub­ stances, hydroxyapatite (HA) has the characteristics of combining and dissociating calcium and phosphate as those of bone. Organic substances include the bone morphogenetic protein (BMP) and proteins with osteoinduction capacity as well as type I collagen, which is the same as alveolar bone itself. Therefore, they have the same bone remodeling capacity…