Abstract
In healthy individuals, plasma cells originating from the bone marrow produce immunoglobulin molecules composed of two heavy chains and two light chains. There are two types of light chains in humans, kappa and lambda. The chapter provides an overview of the history, utility and interpretation of free light chain (FLC) measurement in plasma cell dyscrasias.
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CITATION STYLE
APA
Selvaratnam, R., Cao, J., & Karger, A. B. (2015). Serum free light chain analysis. In Plasma Cell Neoplasms: A Morphologic, Cytogenetic and Immunophenotypic Approach (pp. 25–42). Springer International Publishing. https://doi.org/10.1007/978-3-319-10918-3_2
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