Impact of television coverage on the number and type of symptoms reported during a health scare: A retrospective pre-post observational study

Abstract

Objectives: This study investigated the impact of television news coverage on total adverse event reporting rates 1 month before and after the bulletins during a medication health scare. We further investigated whether individual side effects mentioned in each bulletin were reflected in the adverse event reports following the coverage. Design: A retrospective pre-post observational study. Setting: New Zealand Centre for Adverse Reactions Monitoring. Participants: Adverse events reported from May to December 2008 relating to Eltroxin formulation change. Primary and secondary outcome measures: Primary outcome measure was the total rate of adverse event reporting per day. Secondary outcome measure was the rate of reporting of seven individual symptoms mentioned in the television coverage. Results: After story 1, a significant increase in total reporting rates was evident (Mdn Pre=0, Mdn Post=13.5, U=2, p<0.001, r=-0.86) with larger effect sizes for increases in television-mentioned symptoms. Story 2 also showed a significant increase in total adverse event reporting (Mdn Pre=6, Mdn Post=18.5, U=86.5, p=0.002, r=-0.49) driven by significant increases only in television-reported symptoms. Story 3 did not result in a significant increase in total reporting (Mdn Pre=12; Mdn Post=15.5, U=171, p=0.432, r=-0.12), and showed a significant increase in reporting rates for only one of the two television-reported symptoms. Conclusions: The findings suggest that television news coverage can impact on the overall rate of adverse event reporting during a health scare, in part via increased reporting of media-mentioned side effects. The effects of television media coverage on adverse event reporting appear strongest for earlier reports.