Dynamics of quality of life indicators associated with weight loss in patients with metabolically healthy obesity

Abstract

The purpose of the study was to analyse quality of life (QoL) indicators in patients with metabolically healthy obesity (MHO) associated with ≥ 5% weight loss. Material and Methods - The study involved 44 females with MHO (according to the IDF criteria of the metabolic syndrome (MS), 2005) and 33 females with metabolically unhealthy obesity (MUHO) aged 19-59 years. To assess QoL, we used the SF-36 questionnaire (Medical Outcomes Study - Short Form 36). Results - Initially QoL indicators in both groups were not significantly different statistically. The physical component of health (PHsum) in the MHO and MUHO groups averaged 53.9±6.7 & 50.6±6.3 points (p=0.032). The mental component of health (MHsum) averaged 42.1±1.8 & 45.1±1.8 points (p=0.255). The ≥5% decrease in body weight (from the initial body weight) after 6 months led to an increase in the indicators of physical role functioning by 11.6%, vitality by 12.8%, social functioning by 11.2%, emotional role functioning by 11.9%, mental health by 8.8% (p<0.05) in the MHO group, while in the MUHO group the indicators of physical role functioning increased by 24.6%, emotional role functioning by 39.5%, and mental health by 9.2 % (p<0.05). Conclusion - The MHO group is characterized by higher physical component of health, without a statistically significant difference in the indicators of each of the 8 scales of the SF-36 questionnaire. A ≥ 5% decrease in the body mass in patients of both groups is accompanied by the increase in the indicators of QoL.