In this chapter, we give a short introduction to the genetics of complex diseases emphasizing evolutionary models for disease genes and the effect of different models on the genetic architecture, and we give a survey of the state-of-the-art of genome-wide association studies (GWASs).
CITATION STYLE
Besenbacher, S., Mailund, T., Vilhjálmsson, B. J., & Schierup, M. H. (2019). Association mapping and disease: Evolutionary perspectives. In Methods in Molecular Biology (Vol. 1910, pp. 533–553). Humana Press Inc. https://doi.org/10.1007/978-1-4939-9074-0_17
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