Toxic effects of dichloromethane on the growth of methanotrophic bacteria

Abstract

The effect of a range of dichloromethane (DCM) concentrations on the growth of five obligate methanotrophic bacteria of the genera Methylomonas, "Methylosinus", and Methylocystis was assessed. DCM concentrations of 78 mM were bactericidal for all strains. Concentrations of 7.8 mM-156 μM were bacteriostatic for Methylocystis parvus ACM 3309 and Methylomonas aurantiaca HB2, and partially inhibitory for Methylomonas methanica strains ACM 3307 and HB1. "Methylosinus trichosporium" ACM 3311 grew in the presence of up to 780 μm DCM, but a concentration of 7.8 mM was bacteriostatic. © 1993.