Hydroxylation of dehydroepiandrosterone by Penicillium decumbens ph-13

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Abstract

Dehydroepiandrosterone was hydroxylated by biotranformation with typical Penicillium decumbens ph-13. The two products were obtained and identified by NMR and polarimeter. The results indicate that they are 1α-hydroxy- dehydroepiandrosterone and 7α-hydroxy-dehydroepiandrosterone, respectively. The hydroxylation of dehydroepiandrosterone by Penicillium decumbens ph-13 offers a gentle and promising way of producing the desired compounds that is not available by chemical synthesis. © Springer-Verlag Berlin Heidelberg 2014.

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Zhang, S., Liu, P., Zhao, L., & Liu, X. (2014). Hydroxylation of dehydroepiandrosterone by Penicillium decumbens ph-13. In Lecture Notes in Electrical Engineering (Vol. 251 LNEE, pp. 1393–1398). https://doi.org/10.1007/978-3-642-37925-3_148

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