Composite bioceramics/polymer electrospun scaffolds for regenerative medicine

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Abstract

The main goal of this study was to succeed in the relevant association of well-known osteoconductive biphasic calcium phosphate (BCP) made of Hydroxyapatite (20% HA) and β- Tricalcium Phosphate (80% β-TCP) crystallographic phases and resorbable poly(L-lactide-co-D,Llactide)( PLDLLA) 3D matrices synthesized by electrospinning. Two types of mineral particles were obtained, BCP new hollow granules, and classical BCP particles. It appeared that hollow shells/PLDLLA composite 3D matrices allowed higher cell adhesion in vitro, thanks to internal concavities and are promising scaffolds in terms of cell carrying. © (2013) Trans Tech Publications, Switzerland.

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Miramond, T., Borget, P., Colombeix, C., Baroth, S., & Daculsi, G. (2013). Composite bioceramics/polymer electrospun scaffolds for regenerative medicine. In Key Engineering Materials (Vol. 529–530, pp. 441–446). Trans Tech Publications Ltd. https://doi.org/10.4028/www.scientific.net/KEM.529-530.441

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