TRP channels in the brain

Abstract

In the past few years the presence of one or another member of the TRP channel family has been described basically in all tissues studied. Moreover, the pattern of expression and the susceptibility to modulators of each channel subtype in each tissue will shape their influence on the cell/tissue response. With this idea in mind this review aims to give an overall and updated perspective about the TRP expression research focusing mainly on TRPA1, TRPC, TRPM, and TRPL subfamilies, in nervous tissue, summarizing the data available on the presence of TRP channels and the techniques employed on each study. A comment on their putative function is also provided. © 2012 Springer Science+Business Media, LLC.