Haematocin, a new antifungal diketopiperazine produced by Nectria haematococca Berk. et Br. (880701a-1) causing Nectria blight disease on ornamental plants

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Abstract

A new antifungal diketopiperazine named haematocin was isolated from the culture broth of Nectria haematococca Berk. et Br. (880701a-1) causing blight disease on ornamental plants, Phalaenopsis spp. and Doritanopsis spp. Its structure was established by spectroscopic methods. Haematocin inhibited the germ-tube elongation and spore-germination of Pyricularia oryzae at the ED50 values of 30 μg/ml and 160 μg/ml, respectively.

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Suzuki, Y., Takahashi, H., Esumi, Y., Arie, T., Morita, T., Koshino, H., … Yamaguchi, I. (2000). Haematocin, a new antifungal diketopiperazine produced by Nectria haematococca Berk. et Br. (880701a-1) causing Nectria blight disease on ornamental plants. Journal of Antibiotics, 53(1), 45–49. https://doi.org/10.7164/antibiotics.53.45

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