Obesity, Hypertension, and Dyslipidemia

Abstract

Hypertension and dyslipidemia are closely related with obesity. Obesity releases nonesterified fatty acids into the circulation, increasing fasting plasma triglycerides, reducing high-density lipoprotein cholesterol, and inducing a shift to a proatherogenic composition (small, dense) of low-density lipoproteins. Obesity activates the sympathetic nervous system, increases sodium and water reabsorption, and increases the production of angiotensin II factors that determine hypertension shift in obese people.