The BNT162b2 mRNA Vaccine Elicits Robust Humoral and Cellular Immune Responses in People Living with Human Immunodeficiency Virus (HIV)

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Abstract

Previous studies have shown that certain vaccines induce suboptimal responses in people living with human immunodeficiency virus (HIV, PLWH). However, responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines have not been fully characterized in these patients. Here we show that the BNT162b2 vaccine induces robust immune responses comparable to responses in healthy donors.

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Woldemeskel, B. A., Karaba, A. H., Garliss, C. C., Beck, E. J., Wang, K. H., Laeyendecker, O., … Blankson, J. N. (2022). The BNT162b2 mRNA Vaccine Elicits Robust Humoral and Cellular Immune Responses in People Living with Human Immunodeficiency Virus (HIV). Clinical Infectious Diseases, 74(7), 1268–1270. https://doi.org/10.1093/cid/ciab648

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