A toxicodynamic model (TDM) is used to describe a concentration-response relationship primarily for predicting effects at certain concentrations but also as explanatory tool for investigating mechanisms of action (MOA) of toxic substances or explaining sensitivity differences between exposed subjects. All such information can specifically contribute to the risk assessment of such substances. Suitable mathematical models and statistical analysis methods have to be applied for the toxicodynamic modeling.
CITATION STYLE
Edler, L., & Tritscher, A. (2014). Toxicodynamic models. In Regulatory Toxicology (pp. 261–268). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-35374-1_48
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