Simple two-step ipso substitution of aromatic carboxylic acids by alkyl halides

22Citations
Citations of this article
10Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Methyl-substituted arenes can be synthesized with high regioselectivity in only two steps through formal exchange of an aromatic carboxylic acid function with an alkyl substituent. The results obtained with toluic acid illustrate that good to very good yields can be obtained from inexpensive reagents (see scheme).

Cite

CITATION STYLE

APA

Vorndran, K., & Linker, T. (2003). Simple two-step ipso substitution of aromatic carboxylic acids by alkyl halides. Angewandte Chemie - International Edition, 42(22), 2489–2491. https://doi.org/10.1002/anie.200351087

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free