Dimorphic Fungi in Biology and Medicine

Abstract

"Proceedings of the Fourth Symposium on Topics in Mycology on Fungi Dimorphism, held September 1-4, 1992, in Cambridge, United Kingdom"--Title page verso. Proceedings of the Fourth Symposium on Topics in Mycology on Fungi Dimorphism, jointly organized by the Janssen Research Foundation and the International Society for Human and Animal Mycology, and held in Cambridge, England in September 1992. Following an introductory paper, the remainder of the volume is divided into four sections: molecular genet. Fungal dimorphism: a sideways look -- Molecular genetics of morphogenetic processes -- Molecular controls of conidiogenesis in Aspergillus nidulans -- Physical and genetic mapping of Candida albicans -- Genetic basis for dimorphism and pathogenicity in Candida albicans -- Multiple chitin synthase genes of Candida albicans and other pathogenic fungi -- Key genes in the regulation of dimorphism of Candida albicans -- Switching and the regulation of gene transcription in Candida albicans -- Characterization of Saccharomyces cerevisiae pseudohyphal growth -- Phase transition in Wangiella dermatitidis: identification of cell-division-cycle genes involved in yeast bud emergence -- Morphological aspects of fungal dimorphism -- Mathematical analysis of the cellular basis of fungal dimorphism -- Quantification of Candida morphology in vitro and in vivo. (cont) Nature and control of cell wall biosynthesis -- Possible roles of mannoproteins in the construction of Candida albicans cell wall -- Is there a role for sterols and steroids in fungal growth and transition from yeast to hyphal-form and vice-versa? -- Factors regulating morphogenesis in Coccidioides immitis -- Dimorphism in Histoplasma capsulatum: study of cell differentiation and adaptation -- Biochemical and physiological aspects in the dimorphism of Paracoccidioides brasiliensis -- Studies on phase transitions in Sporothrix schenkii: possible involvement of protein kinase C -- Clues about chromoblastomycotic and other dematiaceous fungal pathogens based on Wangiella as a model -- Dimorphism in mucor species -- Morphological variation in Malassezia and its significance in pityriasis versicolor. (cont) Dimorphism and pathogenesis -- Complement receptors in Candida albicans and other yeasts: structure, function and role in pathogenesis -- Immunogenic and immunomodulatory roles of distinct mannoprotein constituents of Candida albicans -- Structural and antigenic correlates of Histoplasma capsulatum -- Pathogenicity of Wangiella dermatitidis -- Do dimorphic fungi more easily escape host defenses and treatment? -- Diagnosis and treatment of mycoses -- Significance of morphologic form in producing immunodiagnostic antigens for dimorphic fungal pathogens -- Diagnosis of histoplasmosis -- Animal models of mycoses caused by fungi that produce yeast- and hyphal forms -- Morphological aspects of antifungal action -- Dimorphism and candidosis: clinical and therapeutic implications -- Treatment of sporotrichosis, blastomycosis and histoplasmosis. (cont) Azole compounds in the treatment of paracoccidioidomycosis -- Current therapy for coccidioidomycosis -- Treatment of phaeohyphomycosis and pityriasis versicolor -- Penicilium marneffei: dimorphism and treatment.