Antidepressants and testicular cancer: Cause versus association

3Citations
Citations of this article
19Readers
Mendeley users who have this article in their library.

Abstract

ponsible for statistically significant relationships in study designs that are not randomized controlled trials.A data mining study that examined associations between 105 drugs and 55 cancer sites found significant associations between 2 selective serotonin reuptake inhibitors (fluoxetine and paroxetine) and testicular cancer. The study suggested several reasons why these associations merited further investigation. A later study tested specific relationships between 12 antidepressant drugs and testicular cancer and subtypes thereof; whereas significant relationships were again found, these disappeared after adjusting for confounding variables.These 2 studies are educative because they illustrate how false-positive results can easily arise in exploratory research and how confounding may be res. © Copyright 2014.

Cite

CITATION STYLE

APA

Andrade, C. (2014). Antidepressants and testicular cancer: Cause versus association. Journal of Clinical Psychiatry, 75(3). https://doi.org/10.4088/jcp.14f09056

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free