Objective: To compare the effect of repeated boluses of local anaesthetics with an oral analgesic for pain management after tension-free inguinal hernia repair. Design: Prospective randomised study. Setting: University hospital, Germany. Subjects: 104 patients undergoing elective hernia repair. Interventions: 52 patients were given boluses of 0.5% bupivacaine 10 ml through a subcutaneous catheter and 52 dipyrone 500 mg orally 6, 12 and 24 hours after operation. Main outcome measures: Postoperative pain measured on a visual analogue scale, complications, systemic side effects, supplementary analgesics, costs, and time taken to give the analgesics. Results: There were no significant differences between the groups in absolute pain scores, course of pain, and the effects of analgesics. Thirteen patients [5 in the bupivacaine group and 8 in the dipyrone group] required additional dipyrone [mean (range) 2000 mg (500- 5000) and 2500 mg (500-4000) respectively]. There were no systemic side effects of either treatment. There were 5 wound haematomas in the bupivacaine group (10%), and 2 wound haematomas and 1 superficial wound infection in the dipyrone group (6%). Mean costs of material and time taken to give the analgesics were (L) 104.70 and 47 minutes in the bupivacaine group compared with (L) 3.40 and 6 minutes in the dipyrone group. The median (range) hospital stay was 2 (1-3) days in both groups. Conclusions: Repeated boluses of local anaesthetic did not result in better or cheaper pain control than oral analgesics after tension-free inguinal hernia repair.
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Zieren, J., Zieren, H. U., Jacobi, C. A., & Müller, J. M. (1999). Repeated boluses of local anaesthetic for pain relief after inguinal hernia repair. European Journal of Surgery, 165(5), 460–464. https://doi.org/10.1080/110241599750006703