Enhanced nanohydroxyapatite formation using a hydrolyzed gelatin

Abstract

Hydroxyapatite (HAP) nanoparticles were synthesized at room temperature using hydrolyzed gelatin (HG) as an additive. The crystallinity of HAP particles can be effectively controlled by adjusting the concentration of HG additive and the pH value of reaction system. The synthesized product was analyzed by Fourier transform infrared (FTIR) spectrometer, energy dispersive spectrometer (EDS), X-ray diffractometry (XRD), and transmission electron microscope (TEM). Meanwhile, it was proved that, with HG additive, HAP can be prepared with the calcium-phosphorus ratio of not only 1.67 but also 1.50. Conventionally, HAP particles need to be synthesized at high temperature with iCa/P = 1.67. Therefore, we believe that this study provides a novel strategy for the preparation of nano-HAP.