Putting Small Molecules in the Lead

Abstract

Chemical genomic approaches offer an alternative to traditional high-throughput screening for drug discovery and provide an emerging approach to probing cellular biology. The 58th Ernst Schering Foundation Workshop on “Chemical Genomics: Small Molecule Probes to Study Cellular Function, ” held April 6–8, 2005, in Berlin, Germany, cap tured recent chemical genomics advances and highlighted the power of a tight integration of chemistry and biology. © 2005 Nature Publishing Group.