Adjuvant therapies in the treatment of pre-arthritic hip disease

Abstract

Pre-arthritis in the dysplastic hip is a challenging problem. Systemic drug use, such as non-steroidal anti-inflammatory drugs, and intra-articular injection, including corticosteroid and hyaluronic acid injections, are both currently the first-line treatments. Application of platelet-rich plasma and bone marrow aspirate concentrate is gathering special interests among physicians and patients; however, evidence from recent publications is limited. Translational studies using high concentrate stem cells are on-going, and have shown interactive results in the preliminary articles. Applying or regulating growth factors can be a promising frontier in the future. In this chapter, the current and possible future treatment options are introduced with review of previous clinical and translational articles.