This study investigated the effects of microwave radiation on the PVN of the hypothalamus, extracted from rat brains. Expression of c-Fos was used to study the pattern of cellular activation in rats exposed once or repeatedly (ten times in 2 weeks) to 2.45 GHz radiation in a GTEM cell. The power intensities used were 3 and 12 W and the Finite Difference Time Domain calculation was used to determine the specific absorption rate (SAR). High SAR triggered an increase of the c-Fos marker 90 min or 24 h after radiation, and low SAR resulted in c-Fos counts higher than in control rats after 24 h. Repeated irradiation at 3 W increased cellular activation of PVN by more than 100% compared to animals subjected to acute irradiation and to repeated non-radiated repeated session control animals. The results suggest that PVN is sensitive to 2.45 GHz microwave radiation at non-thermal SAR levels. © 2011 Springer Science+Business Media, LLC.
CITATION STYLE
Jorge-Mora, T., Misa-Agustiño, M. J., Rodríguez-González, J. A., Jorge-Barreiro, F. J., Ares-Pena, F. J., & López-Martín, E. (2011). The effects of single and repeated exposure to 2.45 GHz radiofrequency fields on c-fos protein expression in the paraventricular nucleus of rat hypothalamus. Neurochemical Research, 36(12), 2322–2332. https://doi.org/10.1007/s11064-011-0557-4
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