Traditional Chinese medicine (TCM) plays an indispensable role in cancer prevention and treatment. Chinese herbal medicine (CHM) is a key component of TCM and has been practiced for thousands of years. A number of naturally occurring products from Chinese herbs extracts exhibit strong inhibitory properties against carcinogenesis, including CHM single-herb extracts, CHM-derived active components, and CHM formulas (the polyherbal combinations), which regulate JAK/STAT, MAPK, and NF-κB pathways. The present review aims to report the cancer-preventive effect of CHM with evidence from cell-line, animal, epidemiological, and clinical experiments. We also present several issues that have yet to be resolved. In the future, cancer prevention by CHM will face unprecedented opportunities and challenges.
CITATION STYLE
Jiao, L., Bi, L., Lu, Y., Wang, Q., Gong, Y., Shi, J., & Xu, L. (2018, January 8). Cancer chemoprevention and therapy using Chinese herbal medicine. Biological Procedures Online. BioMed Central Ltd. https://doi.org/10.1186/s12575-017-0066-1
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