Personal values in adolescence and their associations with metabolic biomarkers in adulthood: A Japanese population-based study

Abstract

Background: Personal values, which are formed in early life, can have an impact on health outcome later in life. Objective: The aim of this study is to investigate the relation between personal values in adolescence and bio-indicators related to metabolic syndrome (MetS) in adulthood. Participants and Methods: The longitudinal data used was from the Japanese Study on Stratification, Health, Income, and Neighborhood (J-SHINE). Personal values in adolescence were retrospectively obtained in 2017 from a self-reporting questionnaire, composed of value priorities and commitment to the values. Venous samples were collected in 2012 for low and high-density lipoprotein (LDL, HDL) cholesterol and hemoglobin A1c (HbA1c). Body mass index (BMI), waist circumference and systolic and diastolic blood pressure (SBP, DBP) were also measured. The associations of each variable were examined by partial correlation analysis. In addition, multiple linear regression analysis was conducted to examine overall associations between personal values and the sum of standardized scores (Z-score) of the biomarkers as a proxy of MetS. Results: The total population (n = 668) included 261 men and 407 women. For men, the personal value priority of "Having influence on society"was associated with high HDL cholesterol (0.133, p = 0.032) and "Cherishing familiar people"with low waist circumference (r =-0.129, p = 0.049), low SBP, and high DBP (r =-0.135, p = 0.039; r = 0.134, p = 0.041). For women, "Not bothering others"was associated with high SBP and low DBP (r = 0.125, p = 0.015; r =-0.123, p = 0.017). "Economically succeeding"was associated with a worse outcome (β = 0.162, p = 0.042) in men. Conclusions: Although some significant associations were found between personal values in adolescence and MetS-related markers in adulthood, the overall associations were not strong. Culturally prevailing values were likely to be associated with a good outcome of metabolic health.