In this issue of Blood, Jacquelin et al report that loss of DNA methyl-transferase 3A (Dnmt3a) in hematopoietic cells expressing mutant Jak2V617F promotes progression from polycythemia vera to myelofibrosis leading to bone marrow failure and premature mortality.
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CITATION STYLE
Skoda, R. C. (2018). Accelerating myelofibrosis through loss of Dnmt3a. Blood, 132(26), 2703–2704. https://doi.org/10.1182/blood-2018-11-883470