Laser Doppler flowmetry is a noninvasive technique commonly used to monitor skin perfusion after free-tissue transfer or replantation in reconstructive surgery. Several investigators have expressed concern about the reliability of the quantitative value provided by laser Doppler flowmeters (LDF) and the extent to which they reflect nutrient blood flow. This experiment was designed to compare quantitatively the skin blood flow in the pig measured by LDF and by 15-pm radioactive microspheres (RMs). It was observed that the skin blood flow rates measured by LDF and RMs in the normal skin and in acute ran- dom-pattem and arterialized skin flaps were highly correlated (r = 0.93, P < 2 mL/min/100 g). We speculated that the LDF most likely measured both nutrient and arteriovenous shunt flow in the skin and that this arteriovenous shunt flow at least in part caused the discrepancy in skin blood flow rates measured by the LDF and RMs because the 15-pm RMs are known to measure nutrient blood flow only. The inherent variations and errors in LDF technique were also discussed. © The American Laryngological, Rhinological & Otological Society, Inc.
CITATION STYLE
Rival, R., Bance, M., Antonyshyn, O., Phillips, J., & Pang, C. Y. (1995). Comparison of laser doppler flowmeter and radioactive microspheres in measuring blood flow in pig skin flaps. Laryngoscope, 105(4), 383–386. https://doi.org/10.1288/00005537-199504000-00009
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