Controlled cold induced lipolysis

Abstract

While liposuction is still the gold standard for body contouring, controlled cold induced lipolysis is an effective option for patients interested in nonsurgical procedures. Controlled cold lipolysis is produced via a proprietary device that cools tissue to approximately 0 °C and results in crystallization of intracellular lipids within adipocytes with subsequent apoptosis, panniculitis, and reduction of adipocytes. Reduction in adipose tissue apparent by improvement in body surface contours is clinically evident 2-4 months following treatment. Controlled cold lipolysis received its FDA clearance for treatment of flanks in 2010, abdomen in 2012, and thighs in 2014. Studies have reproducibly shown high patient satisfaction with this technology and the incidence of severe side effects is low. The ideal candidate for this device is a patient with discrete area(s) of redundant adipose tissue and skin without laxity. We feel appropriate patient selection is the key to obtaining best results following controlled cold induced lipolysis.