The aberrations in B-cell growth signaling that characterize aggressive B-cell lymphomas, including large B-cell lymphoma and mantle cell lymphoma, are discussed. The shift from paracrine to autocrine growth factor expression and the subsequent dysregulation of multiple ligand-receptor pathways are highlighted.
CITATION STYLE
Pham, L. V., & Ford, R. J. (2010). Growth Signaling and Survival Pathways in Aggressive B-cell Lymphoma. In Neoplastic Hematopathology (pp. 563–572). Humana Press. https://doi.org/10.1007/978-1-60761-384-8_34
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