The single-chain twin-cassette ABC-ATPase RLI resembles other ABC nucleotide binding domains (Karcher et al., 2005, this issue of Structure), but seems to convey its mechanochemical ATP-dependent signals through a novel "hinge" region and/or an N-terminal FeS cluster, at sites where other ABC-ATPases have regulatory domains. ©2005 Elsevier Ltd. All rights reserved.
Lebbink, J. H. G., & Sixma, T. K. (2005). Variations on the ABC. Structure. Cell Press. https://doi.org/10.1016/j.str.2005.03.003