Clinical/methodical issue: Neuroendocrine tumors (NET) of the stomach, duodenum and pancreas are rare tumors with a low incidence but the exact tumor localization and staging diagnostics are of critical importance for further planning of treatment. Standard radiological methods: Standard primary diagnostic methods include multimodal imaging with computed tomography (CT) and magnetic resonance imaging (MRI) but in 20–50% of the cases the localization of the primary tumor cannot be identified. Methodical innovations: Modern hybrid imaging procedures combine radiological procedures and functional imaging, e.g. using somatostatin receptor (SSR) positron emission tomography CT (PET)/CT imaging. For the exact diagnostics of the primary tumor and distant metastases morphological and functional aspects can be combined for targeted diagnostics. For primary tumor staging a sensitivity of 80.0% and a specificity of 88.4% are given in the literature. Performance: The application of SSR PET/CT led to a change in patient management in 44% of all cases according to a recently published meta-analysis and therefore had a significant influence on the further procedure. Assessment: The use of SSR PET/CT can provide critical information for further treatment and can lead to a significant change in treatment management in a relevant proportion of patients. Practical recommendations: Radiological imaging diagnostics and in particular hybrid functional imaging procedures using PET/CT will become increasingly more relevant for the diagnostics, treatment and follow-up of NET patients.
CITATION STYLE
Rübenthaler, J., Auernhammer, C., Harun, I., Ricke, J., & Cyran, C. C. (2019, November 1). Neuroendocrine tumors of the stomach, duodenum and pancreas: Value of (hybrid) radiological diagnostics. Radiologe. Springer Verlag. https://doi.org/10.1007/s00117-019-00593-1
Mendeley helps you to discover research relevant for your work.