First Case Report of Human Granulocytic Anaplasmosis In Mexico With Serological and Molecular Evidence

Abstract

Human Granulocytic Anaplasmosis in a tick-borne rickettsial disease casused by Anaplasma phagocytophilum, and transmited by Ixodes scapularis tick. Since the first recognition in 1990 in United States, theres no evidence of human cases in Mexico dispited the vector and reservoirs are reported already. We report the first case of Human Granulocytic Anaplasmosis in Mexico with serological and molecular evidence. Human Granulocytic Anaplasmosis (HGA) is an emerging tick- borne rickettsial disease, caused by Anaplasma phagocytophilum; a Gram-negative intracelular bacteria. The first recognition of A. phagocytophilum was 1990 in United States [1]. Seroepidemiological rates in endemic areas are as hight as 15-36% [2]. A. phagocytophilum is transmited by Ixodes scapularis ticks, as the principal competent vector, and Peromyscus leucopus mice as a major host reservoir in the wild cycle. Until now theres no evidence of mexican cases have been previously reported dispited the vector and reservoirs are reported in Mexico [3,4]. We present the first case of HGA acquired in a rural area from Estado de Mexico, Mexico.