Vitamin D deficiency has been related with a rise in blood pressure values. An increase in renin-angiotensin-aldosterone system activity, endothelial dysfunction, calcium homeostasis modifications, a rise in oxidative stress and reduction in prostaglandins production appear to be the main pathophysiological mechanisms associated in patients with low vitamin D levels and high blood pressure values. The use of supplements of vitamin D for reducing the risk or progression of hypertension could be a choice for patients with low levels of this vitamin. Low levels of vitamin D have been related with a failure in antihypertensive treatment, and further evaluation of efficacy of antihypertensive treatment in patients with low levels of this substance should be continued.
CITATION STYLE
Castro Torres, Y., Fleites Pérez, A., Carmona Puerta, R., Vega Valdez, M., & Santiestebán Castillo, I. (2014, September 6). Déficit de la vitamina D e hipertensión arterial. Evidencias a favor. Revista Colombiana de Cardiologia. Elsevier B.V. https://doi.org/10.1016/j.rccar.2015.06.005
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