Cellular systems produce reactive oxygen species during the process of metabolism. Oxidative stress results in the activation or repression of many genes in important signaling pathways. DNA microarrays allow for a high throughput evaluation of the changes in gene expression levels in any biological system. In this study, we describe a method to employ gene expression microarrays to study the transcriptional changes in redox-engineered cell lines that will overexpress MnSOD and/or catalase in the mitochondria. © 2009 Humana Press.
CITATION STYLE
Subbaram, S., Melendez, J. A., & Chittur, S. V. (2008). Method for conducting microarray study of oxidative stress induced gene expression. Methods in Molecular Biology, 477, 357–368. https://doi.org/10.1007/978-1-60327-517-0_27
Mendeley helps you to discover research relevant for your work.