The insulin-like growth factor (Igf) binding protein (Igfbp) family has a broad range of physiological functions and a fascinating evolutionary history. This review focuses on the Igfbps of teleost fishes, where genome duplication events have diversified gene repertoire, function, and physiological regulation-with six core Igfbps expanded into a family of over twenty genes in some lineages. In addition to briefly summarizing the current state of knowledge on teleost Igfbp evolution, function, and expression-level regulation, we highlight gaps in our understanding and promising areas for future work.
CITATION STYLE
de la Serrana, D. G., & Macqueen, D. J. (2018, March 12). Insulin-like growth factor-binding proteins of teleost fishes. Frontiers in Endocrinology. Frontiers Media S.A. https://doi.org/10.3389/fendo.2018.00080
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