A novel concept for triggering conformational transitions, and thus changes in structure and function, in peptides with a switching element S provides intriguing perspectives for studying molecular processes (see scheme) that play a key role, for example, in early events of Alzheimer's disease.
CITATION STYLE
Mutter, M., Chandravarkar, A., Boyat, C., Lopez, J., Dos Santos, S., Mandal, B., … Tuchscherer, G. (2004). Switch peptides in statu nascendi: Induction of conformational transitions relevant to degenerative diseases. Angewandte Chemie - International Edition, 43(32), 4172–4178. https://doi.org/10.1002/anie.200454045
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