Abstract
We performed whole exon sequencing of TP53 and PIK3CA genes from the plasma DNA of 17 metastatic breast cancer patients using next generation sequencing. We identified 13 mutations, 7 of which were acquired mutations. Patients with TP53 or PIK3CA mutations in plasma DNA had a significantly (P
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Nakauchi, C., Kagara, N., Shimazu, K., Shimomura, A., Naoi, Y., Shimoda, M., … Noguchi, S. (2016). Detection of TP53/PIK3CA Mutations in Cell-Free Plasma DNA From Metastatic Breast Cancer Patients Using Next Generation Sequencing. Clinical Breast Cancer, 16(5), 418–423. https://doi.org/10.1016/j.clbc.2016.05.004
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