Modulation of Systemic Immune Responses Through Genital, Skin, and oral Microbiota: Unveiling the Fundamentals of Human Microbiomes

Abstract

The human system is encountered by several microbes within and on the external surface of the cells. The prevalence of microbes is more compared to the body cells. The microbial organisms have both beneficial and harmful effects on the system. Studying the microbiome of the system is an accessible and escalating field of research. These organisms eventually involve in modulation. Many studies reported the presence of microbes in the gut, vaginal, oral, skin, urinary, and on the lining of the respiratory tract. Factors such as external environment, internal modulation, and epidemiological factors signify the distinct function and composition of microbes. It is necessary to understand the topography, mecha­nism, and action of microbes so that it would be beneficial to known the pathophysiology, alteration of metabolic events, and progression of many diseases which may pave a pathway for biomarker discovery or drug delivery that can cure or treat or manage the disease with clinical practices.