Here a young patient (< 21 years of age) with a history of infective dermatitis is described. The patient was diagnosed with myelopathy associated with HTLV-1/tropical spastic paraparesis and treated with interferon beta-1a. The disease was clinically established as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and laboratory tests confirmed the presence of antibodies to HTLV-1 in the cerebrospinal fluid (CSF). Mumps, cytomegalovirus, Epstein-Barr virus, schistosomiasis, herpes virus 1 and 2, rubella, measles, varicella-zoster toxoplasmosis, hepatitis, HIV, and syphilis were excluded by serology. The patient was diagnosed with neurogenic bladder and presented with nocturia, urinary urgency, paresthesia of the lower left limb, a marked reduction of muscle strength in the lower limbs, and a slight reduction in upper limb strength. During the fourth week of treatment with interferon beta-1a, urinary urgency and paresthesia disappeared and clinical motor skills improved.
CITATION STYLE
Viana, G. M. de C., da Silva, M. A. C. N., Souza, V. L., Lopes, N. B. da S., da Silva, D. L. F., & Nascimento, M. do D. S. B. (2014). Tratamento com interferon beta-1a em mielopatia associada ao HTLV-1/paraparesia espástica tropical: Relato de caso. Revista Do Instituto de Medicina Tropical de Sao Paulo, 56(5), 443–445. https://doi.org/10.1590/S0036-46652014000500013
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