Antibiotic-resistant gram-negative bacterial infections in patients with cancer

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Abstract

Patients with cancer are at high risk for infections caused by antibiotic resistant gram-negative bacteria. In this review, we summarize trends among the major pathogens and clinical syndromes associated with antibiotic resistant gram-negative bacterial infection in patients with malignancy, with special attention to carbapenem and expanded-spectrum β-lactam resistance in Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Stenotrophomonas maltophilia-all major threats to our cancer patients. Optimal therapy for these antibiotic-resistant pathogens still remains to be determined.

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Perez, F., Adachi, J., & Bonomo, R. A. (2014). Antibiotic-resistant gram-negative bacterial infections in patients with cancer. Clinical Infectious Diseases, 59, S335–S339. https://doi.org/10.1093/cid/ciu612

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