Localized pretibial myxedema is a dermopathy whose treatment is a challenge in dermatology, occurring in 0.5–4% of patients with Graves’ disease. This autoimmune thyroid condition stimulates the production of hyaluronic acid and glycosaminoglycans that are deposited particularly in the pretibial region. Clinically, it presents as a localized, circumscribed, and non-depressible infiltrate in plaques. Several treatment modalities have been proposed, and their results vary, with worse response observed in severe cases. This report presents the case of a patient with elephantiasic pretibial myxedema who was subjected to intralesional corticosteroid applications, resulting in an excellent and encouraging therapeutic response that was maintained.
CITATION STYLE
Ferreira, M., Zacaron, L. H., Valle, A. F. do, & Gamonal, A. C. C. (2020). Successful therapeutic approach in a patient with elephantiasic pretibial myxedema. Anais Brasileiros de Dermatologia, 95(4), 469–472. https://doi.org/10.1016/j.abd.2019.02.007
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