Basal cell carcinoma

Abstract

The incidence of nonmelanoma skin cancer (NMSC) continues to increase now.Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) represent the vastmajority of the malignant tumors. BCC is the most common malignant neoplasm inhumans and its incidence has increased over the last decades. The three main clinicaltypes of BCC are superficial, nodular, and infiltrative (morphea-form and nonmorphoeaform).Until now, there are no clear guidelines for follow-up after an index nonmelanomaskin cancer. The treatments are available for BCC including cryotherapy, topicalchemotherapy, curettage and electrodesiccation, photodynamic therapy, surgical excision,Mohs micrographic surgery, and irradiation. Some factors, including the size, location onthe body, microscopic pattern of the tumor, and others, affect the choice of treatment.Mohs micrographic surgery has the lowest recurrence rate among treatments, but is bestconsidered for large, high-risk tumors. Surgical excision, electrodesiccation andcurettage, or cryotherapy can be used for treatment of smaller, lower-risk tumor.Furthermore, topical imiquimod and fluorouracil are also potential, but less supportedtreatments.