Diagnosis of graves' orbitopathy

Abstract

The diagnosis of Graves' orbitopathy is based on a typical clinical presentation, supported by a family history of Graves' disease, in combination with typical findings on CT or MRI scans and/or elevated serum levels of TSH-receptor-binding immunoglobulins and anti-thyroid peroxidase. In order to treat patients with Graves' orbitopathy, not only the diagnosis, but also the severity and activity scores have to be assessed. The impact of a diagnosis of Graves' orbitopathy should not be underestimated. The disease-specific quality-of-life questionnaire for patients with Graves' orbitopathy, the so-called GO-QOL, is very helpful to perceive the disease from the patient's point of view.