Flow modeling of hollow fiber dialyzers

Abstract

Renal replacement therapies keep the same principles that guided the first dialysis session performed by Kolff in 1943 over a human patient. Despite the interest to build an artificial kidney that replicate better the complex dynamics of the human kidneys, this task is still very immature. However, therapies based on artificial kidneys could improve the clinical outcomes if professionals could predict better their performance. This chapter shows the state of the art concerning this subject, following a top-down approach. © 2013 Springer-Verlag Berlin Heidelberg.