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Journal ArticleOPEN ACCESS

Acid precipitation of Clostridium botulinum type C and D toxins from whole culture by addition of ribonucleic acid as a precipitation aid

Infection and Immunity (1978) 19(2) 749-751
DOI: 10.1128/iai.19.2.749-751.1978
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Abstract

The ratios of ribonucleic acid to protein contents of C. botulinum type C, D, and E cultures were lower than those of type A, B, and F cultures. Addition of ribonucleic acid at 0.4 mg/ml to culture satisfactorily aided acid precipitation of type C and D toxins but not that of type E toxin.

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Iwasaki, M., & Sakaguchi, G. (1978). Acid precipitation of Clostridium botulinum type C and D toxins from whole culture by addition of ribonucleic acid as a precipitation aid. Infection and Immunity, 19(2), 749–751. https://doi.org/10.1128/iai.19.2.749-751.1978

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